What is biomolecular magnetic resonance?

Biomolecular magnetic resonance spectroscopy is of central importance for the determination of structure and function of biological macromolecules including proteins, RNA, and DNA. After the determination of the human genome, the gene products are in the focus of research interest, especially their structure. Structure is the link between the genetic information, encoded in the DNA sequence and translated into protein sequence, and the biological function of the gene products. The importance of magnetic resonance spectroscopy has been honored by the Nobel prizes awarded to Prof. Ernst (1991) and Prof. Wuethrich (2003), ETH Zuerich. The BMRZ is a partner in the European Large Scale MR facilities in Florence and Utrecht and participates in a large number of European Structural Proteomics projects. Structural Biology is also of importance for the development of novel drugs. The BMRZ is involved in joined projects with industrial partners.

What is the Center for biomolecular magnetic resonance?

Frankfurt is an internationally recognized center for magnetic resonance spectroscopy. Four groups Glaubitz, Prisner, Doetsch, and Schwalbe work in the field of NMR and EPR-spectroscopy in the solid and liquid state. Research groups at the Max-Planck-Institutes and the Georg-Speyer-Haus further support Frankfurts leading position worldwide in the field of structural biology (MR-based (Uni Frankfurt) and X-ray- and Cryo EM-based Structural Biology (MPI Biophysics)).

BMRZ is integrated in the international research community. It has close contact, collaborations and shared projects with the other magnetic resonance centers in the EU (Florence, Utrecht and Wageningen) as well as to European research groups at the ETH Zuerich, Oxford/UK, the EPFL Lausanne or to US Research groups at the MIT, University Harvard, University of Yale and many others. For further details see our site Collaborations. The participation in international and national research projects are listed in the Funding list.



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Druckversion: 23. Juli 2010, 13:59